Secretaries of Defense
- George Catlett Marshall (1880–1959), a native of Pennsylvania but a resident of Virginia when appointed by Harry S. Truman, served September 21, 1950–September 12, 1951.
Secretaries of State
- Thomas Jefferson (1743–1826), appointed by George Washington and served March 21, 1790–December 31, 1793.
- Edmund Randolph (1753–1813), appointed by George Washington and served January 2, 1794–August 19, 1795.
- John Marshall (1755–1835), appointed by John Adams and served June 6, 1800–March 4, 1801.
- James Madison (1751–1836), appointed by Thomas Jefferson and served May 2, 1801–March 3, 1809.
- James Monroe (1758–1831), appointed by James Madison and served April 6, 1811–September 30, 1814, and February 28, 1815–March 3, 1817. He also served as temporary secretary October 1, 1814–February 28, 1815.
- Abel Parker Upshur (1790–1844), appointed by John Tyler and served July 24, 1843–February 28, 1844, when he was killed in an explosion aboard USS Princeton.
- Edward Reilly Stettinius Jr. (1900–1949), a native of Illinois but a resident of Virginia when appointed by Franklin Delano Roosevelt; continued in office by Harry S. Truman and served December 1, 1944–June 27, 1945.
- George Catlett Marshall (1880–1959), a native of Pennsylvania but a resident of Virginia when appointed by Harry S. Truman, served January 8, 1947–January 20, 1949.
- Lawrence Sidney Eagleburger (1930–2011), a native of Wisconsin but a resident of Virginia when appointed by George W. Bush, served ad interim August 23, 1992–December 8, 1992, and as secretary December 8, 1992–January 19, 1993.
Secretaries of the Treasury
- Carter Glass (1858–1946), appointed by Woodrow Wilson and served December 16, 1918–January 31, 1920.
- Henry Hamill Fowler (1908–2000), appointed by Lyndon Baines Johnson and served April 1, 1965–December 20, 1968.
- John William Snow (1939– ), appointed by George Walker Bush and served February 3, 2003–June 29, 2006.
Secretaries of War
The Department of War was created by Congress in 1789. It was renamed the Department of the Army and with the Departments of the Navy and Air Force became part of the newly created Department of Defense in 1947, under the cabinet-level secretary of defense.
- James Monroe (1758–1831), appointed by James Madison and served as temporary secretary January 1–February 5, 1813, and September 4, 1814–October 1, 1814, and as secretary October 1, 1814–February 28, 1815.
- James Barbour (1775–1842), appointed by John Quincy Adams and served March 7, 1825–May 26, 1828.
- John Buchanan Floyd (1806–1863), appointed by James Buchanan and served March 6, 1857–December 29, 1860.
Attorneys General
- Edmund Randolph (1753–1813), appointed by George Washington and served February 2, 1790–January 2, 1794.
- Charles Lee (1758–1815), appointed by George Washington and continued in office by John Adams and served December 10, 1795–March 3, 1801.
- William Wirt (1772–1834), a native of Maryland but a resident of Virginia when appointed by James Monroe and served November 15, 1817–March 3, 1829.
- John Young Mason (1799–1859), appointed by James Knox Polk and served March 11, 1845–September 9, 1846.
Postmasters General
The United States Postal Service became an independent agency and the postmaster general ceased to be a cabinet secretary on July 1, 1971.
- James William Marshall (1843–1911), appointed by Ulysses Simpson Grant and served July 7–August 23, 1874.
Secretaries of the Navy
The Department of the Navy was created by Congress in 1798. With the Departments of the Army and Air Force, it became part of the newly created Department of Defense in 1947, under the cabinet-level secretary of defense.
- Abel Parker Upshur (1790–1844), appointed by John Tyler and served October 11, 1841–July 23, 1843.
- Thomas Walker Gilmer (1802–1844), appointed by John Tyler and served February 19–28, 1844, when killed in an explosion aboard USS Princeton.
- John Young Mason (1799–1859), appointed by John Tyler and served March 26, 1844–March 10, 1845; appointed by James Knox Polk and continued in office by Zachary Taylor and served September 9, 1846–March 7, 1849.
- William Ballard Preston (1805–1862), appointed by Zachary Taylor and continued in office by Millard Fillmore and served March 8, 1849–July 22, 1850.
- Claude Augustus Swanson (1862–1939), appointed by Franklin Delano Roosevelt and served until his death, March 4, 1933–July 7, 1939.
Secretaries of the Interior
- Alexander Hugh Holmes Stuart (1807–1891), appointed by Millard Fillmore and served September 16, 1850–March 6, 1853.
- John Barton Payne (1855–1935), appointed by Woodrow Wilson and served March 15, 1920–March 4, 1921.
Secretaries of Labor
- William Nuckles Doak (1882–1933), appointed by Herbert Hoover and served December 9, 1930–March 4, 1933.
