An expedition of colonists led by Sir Richard Grenville leaves England for Roanoke Island.

Five ships and two smaller pinnaces along with 600 men set sail from Plymouth, England, for Roanoke Island, along the present-day Outer Banks of North Carolina. Sir Richard Grenville commands the flagship Tiger, which is piloted by Simon Fernandes. John White, Thomas Hariot, and the Indians Manteo and Wanchese are also present.